Other Brands/Names
Baycuten-N, Bernesten, Beytuce, Candacort, Candazole, Canesten, Cotristen, Fungiderm, Dermifar, Erphamazol, Heltiskin, Katisililine.
How It Works
Clotrimazole is an antifungal medication that works by disrupting the protective barrier of fungal cells. It achieves this by inhibiting the production of ergosterol, which is a key building block in the structure of fungal cells. This disruption prevents fungal growth and ultimately leads to the death of the fungal cells.
Indications
Clotrimazole is used to treat various fungal infections, including:
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Fungal infections of the skin, such as tinea versicolor and ringworm
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Fungal infections of the external ear canal (otitis externa)
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Fungal infections of the female genital tract, such as candidiasis (yeast infection) and trichomoniasis vaginalis
Contraindications
Clotrimazole should not be used by individuals with a known history of hypersensitivity or allergies to the medication. Symptoms of allergic reactions may include hives or swelling of the eyelids.
Side Effects
While side effects are generally rare, some may occur, including:
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Local burning sensation
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Hives or blisters
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Itching
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Peeling skin
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Redness or swelling
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Pain or other signs of irritation
Types
Clotrimazole is available in several forms:
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Cream
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Vaginal tablets (prescription-only)
Dosage
Adult dosage
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Cream
Apply the cream to the affected area 2-3 times daily for 2 weeks, even after the skin condition appears to have healed. Squeeze out a fingertip-sized amount of clotrimazole or as needed and apply to the affected area.
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Vaginal Tablets
Insert two 100 mg vaginal tablets into the vagina for 3 consecutive days, preferably before bedtime.
Children dosage
- Cream
The dosage and administration are the same as for adults.
Safety
Pregnancy:
Clotrimazole is classified as FDA Category B (animal studies have shown no fetal abnormalities, but there are no adequate and well-controlled studies in pregnant women). It is generally considered safe for use during pregnancy, but its use should still be discussed with a healthcare provider.
Drug Interactions
Other topical medications (e.g., tacrolimus): Using clotrimazole with certain topical medications may increase the levels of tacrolimus, raising the risk of side effects.
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- dr Hanifa Rahma
Khatter NJ, Khan MAB. Clotrimazole. [Updated 2021 Jul 12]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK560643/
Mims Indonesia. Clotrimazole. Retrieved 14 January 2022, from: https://www.mims.com/indonesia/drug/info/clotrimazole?mtype=generic
Badan Pengawas Obat dan Makanan. Klotrimazol. Retrieved 14 January 2022, from: https://pionas.pom.go.id/monografi/klotrimazol
Badan Pengawas Obat dan Makanan. Klotrimazol. Retrieved 14 January 2022, from: https://pionas.pom.go.id/monografi/klotrimazol-0
Drugs.com. Clotrimazole. Retrieved 14 January 2022, from: https://www.drugs.com/mtm/clotrimazole-topical.html
Medscape. Clotrimazole. Retrieved 14 January 2022, from: https://reference.medscape.com/drug/gyne-lotrimin-3-combination-pack-gyne-lotrimin-3-vaginal-cream-clotrimazole-342586#0