Other Brands/Names

Benzolac 2.5, Benzolac 5, Benzolac CL, Oxy 5, Flagyl, Acnebenz

How To Work

Benzoyl peroxide is a topical drug / oles that shows the effect of bactericides (antimpactries) on Cutibacterium acnes, bacteria that cause vulgarity (acne) acne. Benzoyl peroxide after being absorbed by the skin will be converted into benzotic acid. About 5% benzoat acid is systemically absorbed and excreted/excreated by the kidney system. The remaining benzoat acid will be metabolized by the system on the skin, releasing oxygen types of active free radicals resulting in oxidation of bacterial proteins. Acne improvement occurs by reducing lipids, free fatty acids, and C. acnes. After using 10% benzoyl peroxide every day for two weeks, the amount C. acnes hair follicles decreased 98%, and the number of free fatty acids decreased 50%, which is comparable to the results obtained after four weeks of antibiotic therapy. Benzoyl peroxide also has a mild sebostatic (reduced oil) effect that contributes to keratolitic activity (lifting dead skin cells and stimulating the regeneration process of skin cells) and is effective in treating comodal acne.

Indications

Benzoyl peroxide is used to treat mild to moderate acne.

Contraindication

The history of allergies to benzoyl peroxide and other benzoat acid derivatives.

Side Effects

• Increased sensitivity to sunlight
• Peeled skin, redness, swelling, or dryness
• The sensation of mild burning, especially at the beginning of the treatment

If any of these effects stay or get worse, consult your doctor. Very serious allergic reactions to this drug are rare. However, get medical help immediately if you experience symptoms of serious allergic reactions, including: rash, itching/swelling (especially in the face/slits/slits), severe dizziness, and difficulty breathing.

Ready

Available in gel form with a concentration of 2.5%-10%.

Dose

Apply 1-2 times a day to the area of the skin that is problematic or according to the instructions listed on the packaging. Start using this drug with a low concentration. Recommendations for doses and use instructions can vary between each product.

Security

• This drug may make you more sensitive to the sun. Avoid exposure to the sun as much as possible. Use sunscreen and wear protective clothing when outdoors.
• Pregnancy: The effect of benzoyl peroxide on reproductive health and fetal health is unknown. However, due to its minimal systemic absorption, the topical benzoyl peroxide application is generally considered safe during pregnancy.
• Breastfeeding: Not much data is available about the use of benzoyl peroxide while breastfeeding. Due to its low level of systemic absorption, minimal risk in infants, and the use of topical benzoyl peroxide is generally considered safe when breastfeeding, as long as the implementation is not in place the baby will have direct contact during breastfeeding or close skin-to-slit contact.

Drug Interaction

Can reduce the effects of tretinoin, isotretinoin, and tazarotene. Can cause temporary color changes in the skin and hair of the face (yellow/orang) if used together with products containing sulfonamide or sulfone.